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Ulipristal Acetate: Review of the Efficacy and Safety of a Newly Approved Agent for Emergency Contraception
Clinical TherapeuticsVol. 34Issue 1p24–36Published online: December 12, 2011- Ashley R. Richardson
- Fraidy N. Maltz
Cited in Scopus: 46Emergency contraception (EC) is used to prevent unintended pregnancies. The current gold standard for oral EC is levonorgestrel (LNG) administered as a single 1.5-mg dose or in 2 doses of 0.75 mg separated by 12 hours. LNG has shown to be effective up to 72 hours after coitus. Ulipristal acetate (UPA) is a selective progesterone receptor modulator approved for EC use in the United States in August 2010. UPA is administered as a one-time, 30-mg dose within 120 hours of intercourse.