This paper is only available as a PDF. To read, Please Download here.
Abstract
Schizophrenia is arguably the worst disease affecting humankind, costly in both social
and financial terms. In the current cost-cutting climate, the focus is on economizing
the delivery of health care, including reducing access to prescription drugs. Yet
decreasing expenditures on drugs for severe illnesses, such as schizophrenia, is a
false economy. Drugs account for only a small proportion of the total costs of treating
schizophrenia, with inpatient hospital care comprising the greatest portion of total
treatment costs. Thus the use of risperidone, a more effective but more expensive
antipsychotic medication, can decrease the total cost of care for patients with chronic
schizophrenia by decreasing the need for hospitalization. Fewer days spent in the
hospital also often means a better quality of life for patients. This finding is illustrated
by case histories of 3 patients, 2 with schizophrenia and 1 elderly patient with behavioral
disturbances of dementia
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical TherapeuticsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Anonymous. Opinion. Where next with psychiatric illness.Nature. 1988; 336: 95-96
- Estimates of the loss of individual productivity from alcohol and drug abuse and from mental illness.in: Frank RG Manning WG Economics and Mental Health. Johnson Hopkins University Press, Baltimore, Md1992: 91-129
- Decision Resources.Depressive Disorders: Cognos Study #8; Pharmacor: Cognos. Decision Resources, Burlington, Mass1992
- Measuring the cost of schizophrenia: Implication for the post-institutional era in the U.S..PharmacoEconomics. 1995; 8: 199-222
- Efficacy and safety of risperidone in the long-term treatment of patients with schizophrenia.Clin Ther. 1995; 17: 402-412
- A report on the “worst” state hospital recidivists in the US.Community Psychiatry. 1992; 43: 904-908
- The economic burden of depression in 1990.J Clin Psychiatry. 1993; 54: 405-418
- Effects of Medicaid drug-payment limits on admission to hospitals and nursing homes.NEJM. 1991; 325: 1072-1077
- Effects of limiting Medicaid drug-reimbursement benefits on the use of psychotropic agents and acute mental health services by patients with schizoprenia.NEJM. 1994; 331: 650-655
- Reduction of hospital days in chronic schizophrenic patients treated with risperidone: A retrospective study.Clin Ther. 1993; 15: 917-926
- Pharmacoeconomic evaluation of long-term treatment with risperidone for patients with chronic schizophrenia.Br J Med Econ. 1996; 10: 59-67
- Reduction in healthcare resource utilisation and costs following the use of risperidone for patients with schizophrenia previously treated with antipsychotic therapy.Clin Drug Invest. 1996; 11: 289-298
- Risperidone—does it give enough bang for the buck.Inpharma. 1994; (April): 7-8
- Cost-effectiveness of clozapine in neuroleptic-resistant schizophrenia.Am J Psychiatry. 1993; 150: 1630-1638
- Evaluating the quality of published pharmacoeconomic evaluations.Hosp Pharm. 1995; 30: 146-153
- The use of generic and specific quality of life measures in hemodialysis patients treated with erythropoietin.Control Clin Trials. 1991; 12 (Suppl 4): 1685-1795
- Quality of life in lung transplant candidates: Effect of education plus exercises vs. education alone.Am Rev Respir Dis. 1992; 145 (Abstract): A477
- Risperidone in the treatment of schizophrenia.Am J Psychiatry. 1994; 151: 825-835
IMS data, February 1996.
- Treating elderly psychiatric patients with risperidone.149th annual meeting of the American Psychiatric Association. 491996; (Presented at the) (New York)
- Risperidone for dementia-related disturbed behavior in nursing home residents: A clinical experience.148th annual meeting of the American Psychiatric Association. 21241995; (Presented at the) (Washington, DC)
- Management of late-life psychosis.J Clin Psychiatry. 1996; 57 (Suppl 3): 39-45
- Behavioral symptoms of Alzheimer's disease: Phenomenology and treatment.J Clin Psychiatry. 1987; 48 (Suppl): 9-15
- Stage specific incidents of potentially remediable behavioral symptoms in aging and Alzheimer's disease: A study of 120 patients using the BEHAVE-AD.Bull Clin Neurosci. 1989; 54: 95-112
- Pharmacologic treatment of Alzheimer's disease: A methodologic critique based upon current knowledge of symptomatology and relevance for drug trials.Int Psychogeriatr. 1992; 4: 9-42
- Assessment of disruptive behavior/agitation in the elderly: Function, methods, and difficulties.J Geriatr Psychiatry Neurol. 1995; 8: 52-60
- Institutionalization of Alzheimer's disease patients: Reducing precipitating factors through family counseling.Home Health Care Serv Q. 1987; 8: 23-51
- Tolerance of disability in elderly dependents by supporters at home: Its significance for hospital practice.BMJ. 1975; 3: 471-473
Article info
Identification
Copyright
© 1997 Published by Elsevier Inc.