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The latest ACC/AHA guidelines on high blood cholesterol management have raised controversy
regarding especially the elimination of the LDL-C treat-to-target strategy and the
adoption of a fixed-dose statin risk reduction strategy. Opponents argue that it could
induce confusion among professionals, decrease in follow-up and patient adherence.
We compared benefits and costs of applying the 2013 ACC/AHA Guidelines, ‘fixed-dose
strategy’, and the 2016 ESC/EAS Guidelines, ‘target strategy’.
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