Abstract
Purpose
The aim of this study was to determine the efficacy and safety profile of tratinterol
hydrochloride tablets in the treatment of bronchial asthma.
Methods
This multicenter, randomized, double-blind clinical research study was completed at
6 centers in the People’s Republic of China from March 2009 to June 2010, and a randomized
trial of procaterol hydrochloride tablets produced by Otsuka Pharmaceutical Co Ltd
was conducted. The study was approved by the Medical Ethics Committee of the First
Hospital of China Medical University. The clinical trial registration number is 2007L04263.
Findings
A total of 223 patients were selected for this study, with 112 patients in the treatment
group and 111 in the control group. The lung function of the 2 groups after treatment
significantly increased in all (P < 0.05); however, there was no significant difference in the changes between the
2 groups (P > 0.05). The occurrence of related adverse events at varying degrees in the control
group was higher than in the treatment group.
Implications
It is safe and effective to use tratinterol hydrochloride tablets to treat bronchial
asthma.
Key words
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Article info
Publication history
Published online: April 06, 2015
Accepted:
March 9,
2015
Identification
Copyright
© 2015 Elsevier HS Journals, Inc. Published by Elsevier Inc. All rights reserved.
