Abstract
Background
Hypertension usually clusters with other cardiovascular risk factors; however, it
has not been reported whether hypertension treatment has an impact on the awareness
and treatment of other cardiovascular risk factors such as diabetes mellitus and hypercholesterolemia.
Objective
To analyze the effect of hypertension treatment on the management of other risk factors
in a Korean population.
Methods
The Korean National Health and Nutrition Examination Survey (KNHANES) was a cross-sectional,
nationally representative survey in which a stratified multistage sampling design
was used. The most recent KNHANES survey, conducted in 2008, was analyzed.
Results
A total of 6547 adults (aged ≥20 years) were included in the analysis. Mean (SD) age
was 49.1 (16.3) years, and 42.0% of the participants were male. The prevalence of
hypertension, hypercholesterolemia, diabetes mellitus, and obesity was 26.9%, 10.5%,
9.5%, and 31.2%, respectively. The prevalence of diabetes mellitus, hypercholesterolemia,
and obesity was significantly higher in the hypertensive group compared with normotensive
participants (P < 0.001). Furthermore, clustering of cardiovascular risk factors was observed in
the patients with hypertension. Treatment of hypertension was significantly associated
with a higher awareness and treatment of diabetes mellitus and hypercholesterolemia,
especially in moderate- to high-risk patients. Moreover, the total cholesterol concentration
and glycosylated hemoglobin levels were significantly lower in the treated hypertensive
patients (P < 0.001 for total cholesterol and P = 0.003 for glycosylated hemoglobin).
Conclusions
Hypertension is a prevalent risk factor and is commonly associated with other cardiovascular
risk factors. In the Korean population, treatment of hypertension can reduce global
risk not only by lowering blood pressure but also by improving the control of other
risk factors, such as diabetes mellitus and hypercholesterolemia.
Key words
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Article info
Publication history
Published online: June 18, 2012
Accepted:
May 23,
2012
Identification
Copyright
© 2012 Published by Elsevier Inc.
