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Abstract
Seventy-nine patients with benign prostatic hyperplasia (BPH) were treated with cernitin
pollen extract. Patient ages ranged from 62 to 89 years (mean, 68 years). Mean baseline
prostatic volume was 33.2 cm3. Cernitin pollen extract was administered in a dosage of 126 mg (2 tablets, 63 mg
each), three times a day, for more than 12 weeks. Symptom scores, based on a modified
Boyarsky scoring scale, uroflowmetry, prostatic volume, residual urine volume, and
urinalysis results were examined before and after administration of cernitin pollen
extract. Symptom scores significantly decreased from baseline, and the favorable results
continued during the treatment period. Urine maximum flow rate and average flow rate
increased significantly from 9.3 mL/s to 11 mL/s and from 5.1 mL/s to 6 mL/s, respectively.
Residual urine volume decreased significantly from 54.2 mL to less than 30 mL. There
was no change in prostatic volume. However, 28 patients treated for more than 1 year
showed a mean decrease of prostatic volume to 26.5 cm3. No adverse reactions were observed. Clinical efficacy at 12 weeks was rated excellent,
good, satisfactory, and poor in 11%, 39%, 35%, and 15% of patients, respectively.
Overall clinical efficacy was 85%. In conclusion, cernitin pollen extract showed a
mild beneficial effect on prostatic volume and urination variables in patients with
symptomatic BPH.
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References
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© 1995 Published by Elsevier Inc.
