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Clinical Therapeutics
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    • Cover Image - Clinical Therapeutics, Volume 45, Issue 4
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  • Research Article

    Initial Experience With Tofacitinib in Clinical Practice: Treatment Patterns and Costs of Tofacitinib Administered as Monotherapy or in Combination With Conventional Synthetic DMARDs in 2 US Health Care Claims Databases

    Clinical Therapeutics
    Vol. 38Issue 6p1451–1463Published online: April 21, 2016
    • James Harnett
    • Jeffrey R. Curtis
    • Robert Gerber
    • David Gruben
    • Andrew Koenig
    Cited in Scopus: 9
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      Tofacitinib is an oral Janus kinase inhibitor indicated for the treatment of rheumatoid arthritis (RA). Tofacitinib can be administered as a monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs (DMARDs). This study describes RA patients’ characteristics, treatment patterns, and costs for those initiating tofacitinib treatment as monotherapy or combination therapy, using US claims data from clinical practice.
      Initial Experience With Tofacitinib in Clinical Practice: Treatment Patterns and Costs of Tofacitinib Administered as Monotherapy or in Combination With Conventional Synthetic DMARDs in 2 US Health Care Claims Databases
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