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Clinical Therapeutics
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    • Cover Image - Clinical Therapeutics, Volume 45, Issue 4
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        Tofacitinib Versus Biologic Treatments in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Tumor Necrosis Factor Inhibitors: Results From a Network Meta-analysis

          Vieira et al.
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  • Research Article
    Open Access

    Tofacitinib Versus Biologic Treatments in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Tumor Necrosis Factor Inhibitors: Results From a Network Meta-analysis

    Clinical Therapeutics
    Vol. 38Issue 12p2628–2641.e5Published online: November 24, 2016
    • Maria-Cecilia Vieira
    • Samuel H. Zwillich
    • Jeroen P. Jansen
    • Brielan Smiechowski
    • Dean Spurden
    • Gene V. Wallenstein
    Cited in Scopus: 43
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      Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This analysis compared the efficacy and safety of tofacitinib with biologic disease-modifying antirheumatic drugs in patients with RA and a prior inadequate response (IR) to tumor necrosis factor inhibitors (TNFi).
      Tofacitinib Versus Biologic Treatments in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Tumor Necrosis Factor Inhibitors: Results From a Network Meta-analysis
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