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Clinical Therapeutics
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    • Cover Image - Clinical Therapeutics, Volume 45, Issue 5
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        Impact of Switching From an Initial Tumor Necrosis Factor Inhibitor on Health Care Resource Utilization and Costs Among Patients With Rheumatoid Arthritis

          Baser et al.
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    • Research Article
      Open Access

      Impact of Switching From an Initial Tumor Necrosis Factor Inhibitor on Health Care Resource Utilization and Costs Among Patients With Rheumatoid Arthritis

      Clinical Therapeutics
      Vol. 37Issue 7p1454–1465Published online: May 18, 2015
      • Onur Baser
      • Arijit Ganguli
      • Sanjoy Roy
      • Lin Xie
      • Mary Cifaldi
      Cited in Scopus: 25
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        Despite improved clinical outcomes for the majority of patients, nearly 30% of patients with rheumatoid arthritis (RA) who initiate tumor necrosis factor antagonist (anti-TNF) biologic agents fail to respond to their first-line anti-TNF and switch to another anti-TNF or a non-TNF biologic. How this change affects health care costs and resource utilization is unknown. We therefore compared RA patients taking first-line anti-TNFs who switched to a second anti-TNF versus those patients who switched to an alternate biologic.
        Impact of Switching From an Initial Tumor Necrosis Factor Inhibitor on Health Care Resource Utilization and Costs Among Patients With Rheumatoid Arthritis
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